A seme is the dominant partner of the uke in a yaoi relationship. The word comes from the verb "to attack."
If the character who has been made the seme is not from a canon that originally has yaoi, it is a very good chance that the character is out of character. If the characters in question do not usually have a structured top/bottom (i.e. dominant/submissive) relationship, but are referred to as seme and uke, that may be considered a charge.
Fandom Examples 
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- Aragorn, being a big filthy man, may be cast as the seme to Legolas' pretty Elven uke.
- Sasuke in "For Your Eyes Only."
- Severus Snape in "Little Miss Mary."
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