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The Tenth Doctor regenerates. Please note the explosive artron energy is not seen in Classic Who.

A Time Lord has thirteen lives all told; when at the end of one life, they can regenerate into a new body. This is a property unique to Time Lords/Ladies. There have been suggestions that some were able to extend the number of regenerations; however, the only known cases of this are the Master, under unusual circumstances – twice by taking over a human (or other non-Time Lord) body, and the third time when he was resurrected and given a new set of regenerations by the Time Lords. This was not, on reflection, a very good idea.

PPC agents who have gone through regeneration include Morgan, the Agent, the Disentangler, the Notarythe Reader, the Guardsman, Tawaki PenguinTadkeeta, Natalie Green, and the Aviator (though the last four were not originally Time Lords).

Time Lord Sues often forget that regeneration has some unpleasant aftereffects, such as manic episodes, fainting spells, confusion, delirium, and poor coordination, among other things. This is a charge.

Spoiler Alert!
This article contains one or more spoilers. This is a potentially bad thing. Be careful reading on if you are not well-versed in the continuum or not caught up!

The Doctor has also been granted an extension in regenerations, as the recent specials have revealed that the Eleventh Doctor actually expended all thirteen lives. The Eighth Doctor apparently regenerated into the War Doctor (John Hurt), who regenerated into Nine, who regenerated into Ten. Ten regenerated during the season four finale, but managed to keep his current face and caused instead a metacrisis – but that was still considered a regeneration in the full scheme of things. Therefore, to regenerate Eleven into Twelve, the Time Lords of Gallifrey, who had been relocated into a parallel dimension instead of being destroyed and were attempting to contact the prime timeline through cracks in space and time, granted Eleven a new set of regenerations.