The Holy Hangover Cure (© Unseen University) is a mixture that the UU wizards cooked up to cure the Oh-God of Hangovers in Terry Pratchett's Hogfather. The Holy Hangover Cure is composed of (among other things): raw eggs, fresh orange juice, Klatchian coffee, mustard, horseradish, cream, anchovies, willow bark, yogurt, Englebert's Enhancer, and a pint bottle of wow-wow sauce. As this would clearly kill any non-godly creatures, and cause godly ones severe-to-nuclear-war-level indigestion, it is firmly recommended that nobody drink this. Ever. At all. Not even to see what happens.
Diocletian uses a tamer version of the HHC in her concoction of Blumble, "in order to distract and dilute the essential aura of Nanny Oggish alcoholic nastiness." The cream is left out, as is Englebert's Enhancer. The wow-wow sauce is available to anybody willing to risk it, but only a couple of drops were in the stuff that Dio gave the SO.
Putting it up against a Pan Galactic Gargleblaster or Pan Galactic Gargle Bleeprin Blaster is likely not advised.