Trigun

Trigun, originally a manga by Yasuhiro Nightow, is well-known as an anime series directed by Satoshi Nishimura. The show follows the adventures of Vash "the Stampede" as witnessed by two insurance workers, Meryl Stryfe and Milly Thompson, who follow him around in an attempt to minimize the damage he causes (mostly by accident) wherever he goes.

In Canon
Vash is a laid-back, doughnut-loving goof who wants nothing more than for everyone to get along with everyone else. Unfortunately, the bounty on his head means he attracts trouble everywhere he goes. He does his best to defuse these situations without killing anyone, and he is suspiciously good at it. Underneath his goofball exterior lurks a dark and mysterious past.